Cytotoxic Study: Effects of Di-ethylhexyl Phthalate and Mono ethylhexyl Phthalate on a Normal Human Lymphocytes Cell Line
The main objective of this study was to determine the toxicity of the phthalates Di-ethylhexyl (DEHP) and its principal metabolite, Mono-ethylhexyl (MEHP) on the TK-6 human lymphoblast cell line. Phthalates are a family of compounds used widely in the manufacturing industry and in the production of plastics. Exposure to these compounds can be through personal and consumer items such as health care and beauty products. Are considered estrogen disrupters but also have been observed effects over the respiratory systems by the scientific community. Studies related with the phthalates exposure have been performed however are limited as well in human cells.
Plasticizer principal metabolite (2 Ethyl-1-Hexanol) effects over the human lymphoblast TK6 cells
The main objective of this study is to determine the toxicity of the 2-Ethyl-1-Hexanol on the TK6 human lymphoblast cell line. The 2-Ethyl-1-hexanol (EH) is an organic alcohol produced in the cells as result of the biotransformation of di-ethylhexyl phthalate (DEHP). The exposure of humans to the compound 2-Ethyl-1-hexanol can be through environmental sources such as paint lacquer, inks, rubber, dry cleaning and plasticizers, e.g. PVC. .